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3701 E Thousand Oaks Blvd. Thousand Oaks, CA 91362

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Chronic Fatigue Syndrome and Fibromyalgia

Millions of Americans are affected by chronic fatigue syndrome and fibromyalgia every year. The two conditions are different but often coexist. Symptoms often include cognitive dysfunction, sleep disturbances, severe fatigue, widespread muscle and body pain and infections. These symptoms may first appear after an illness, infection or period of stress. Patients with severe fatigue may be diagnosed with chronic fatigue syndrome while those who suffer more severe pain may be diagnosed with fibromyalgia.

Both chronic fatigue syndrome and fibromyalgia have been associated with hypothalamic, thyroid and pituitary dysfunction and hormonal deficiencies, which can trigger significant symptoms and interfere with normal daily function. Patients may also suffer from nutritional and neurotransmitter deficiencies and abnormalities due to their conditions.

Because chronic fatigue syndrome and fibromyalgia can be difficult to diagnose with standard blood tests, many who suffer from them are not diagnosed or are inadequately treated. However, with appropriate treatment, patients can continue to live healthy, active lives. Special tests can help identify low hormone levels or inadequate function and can point the way to the most appropriate treatment regimen for you.

Adrenal Gland Function

Adrenal insufficiency or fatigue is common in patients with chronic fatigue syndrome and fibromyalgia. However, other deficiencies may coexist along with the adrenal insufficiency, which means that all areas of concern should be carefully tested and evaluated in order to make appropriate treatment and supplementation recommendations. Proper adrenal support may require both hormonal and nutritional supplementation and lifestyle changes.

Immune System Support

Chronic infections can be a hallmark of chronic fatigue syndrome and fibromyalgia. Symptoms can remain long after the infection has been addressed if the organisms produced neurotoxins. Addressing immunological defects is critical to combating the infections and any long-term effects. Hypothalamic-pituitary axes abnormalities should also be treated.

Hormonal Balance

Patients with hormonal imbalances can experience widespread symptoms, and an imbalance may trigger other imbalances. Individualized treatments can help support hypothalamic, adrenal and pituitary function, restore health balance and promote better symptom control and overall health.

Thyroid and Pituitary Dysfunction

The brain is responsible for producing thyroid stimulating hormone, or TSH, which triggers the secretion of T4 by the thyroid gland. T4 is then converted into the usable form of the hormone, T3. Hypothyroidism is generally diagnosed when the levels of T3 and T4 are low. Unfortunately, other symptoms can also indicate the presence of hypothyroidism even if the levels of T3 and T4 appear to be normal, particularly in patients with fibromyalgia or CFS. Exposure to stress, certain bacteria, viruses, toxins, pesticides and yeast can trigger thyroid dysfunction and symptoms such as brain fog, depression, fatigue, muscle aches and pains and weight gain. Patients with low thyroid levels may also be at an increased risk of heart disease.

Thyroid Resistance will also trigger symptoms even though all tests may return with normal levels of T3 and T4. The thyroid and pituitary glands may be functioning normally, but the body is unable to use the hormones appropriately. This results in symptoms of hypothyroidism. This condition can be triggered or exacerbated by stress, high levels of cortisol, high homocysteine levels and genetic factors.

Treatment Options

If you have been diagnosed with CFS or fibromyalgia, a personalized treatment regimen can help ease discomfort, boost energy levels and improve your overall quality of life. Nutritional supplements can be used to enhance and support natural immune function and combat free radicals that can cause widespread damage particularly in the immune system.

Many people with fibromyalgia or CFS struggle with low levels of vitamin B12. If your thyroid or adrenal glands are not functioning properly, the body may be unable to adequately absorb and use vitamin B12, which makes supplementation critical. Vitamin B12 supports healthy nervous system functioning and can combat the fatigue and depression that often accompany these chronic conditions.

Co-enzyme Q-10 may also be appropriate for some patients. CoQ10 helps produce energy at the cellular level. It can combat symptoms of fatigue and muscle pain. Higher doses may be necessary to achieve desired results, and some patients may need several daily doses in an easy-to-use form for maximum benefit.

D-ribose is a simple sugar and natural energy molecule that can boost mitochondrial energy. Patients with CFS and fibromyalgia often suffer from a lack of energy and profound fatigue. D-ribose can give them the extra boost they need to get through their days.


Individualized therapy can address your unique symptoms and needs. Hormone replacement therapy, nutritional supplementation and other treatments may be necessary as part of your comprehensive treatment program. We can compound the supplements and nutraceuticals you need in easy-to-use dosage forms and your doctor’s requested dosages for completely personalized treatments. Contact us today to learn more about how we can help you restore hormonal balance and improve overall function.


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3701 E Thousand Oaks Blvd. Thousand Oaks, CA 91362 | Toll Free: (800) 991-6509 | Fax: (866) 902-8341


Paseo Oaks Pharmacy is a licensed compounding pharmacy that only engages in compounding in response to a physician's prescription. A written prescription from a licensed physician is required for compounded medication. The information on the site is general in nature and is only intended for use as an educational tool. You should consult your physician or a Paseo Oaks Pharmacy pharmacist if you have any specific questions relating to the diagnosis and treatment of any health problems. Information and statements about products and health conditions have not been evaluated by the Food and Drugs Administration (FDA), nor has the FDA approved the products to diagnose, cure or prevent disease.

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